Measurement system for noninvasive dynamic optical topography

Yuichi Yamashita; Atsushi Maki; Hideaki Koizumi

doi:10.1117/1.429940

1 October 1999 Measurement system for noninvasive dynamic optical topography

Yuichi Yamashita, Atsushi Maki, Hideaki Koizumi

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Journal of Biomedical Optics, Vol. 4, Issue 4, (October 1999). https://doi.org/10.1117/1.429940

We have developed a 24-channel simultaneous measurement system for optical topography that noninvasively obtains dynamic images of brain activity using near-infrared light. To evaluate the system performance, we utilized a dynamic phantom containing a rotating absorber in a cylindrical scattering medium. In this system, eight incident and eight detecting optical fibers are arranged alternately at square lattice points on the phantom. The phantom is illuminated with light of two wavelengths (780 and 830 nm) from each incident fiber. Reflected light is received by the detecting fibers, each of which is connected to an avalanche photodiode. Multiple light intensity modulation and lock-in detection are used to enable highly sensitive measurement with negligible cross talk for multichannel measurement. In the phantom measurement, we obtained topographic dynamic images of the absorber rotating in the medium with a temporal resolution of 0.5 s over a measurement area of 90 mmx90 mm.

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Yuichi Yamashita, Atsushi Maki, and Hideaki Koizumi "Measurement system for noninvasive dynamic optical topography," Journal of Biomedical Optics 4(4), (1 October 1999). https://doi.org/10.1117/1.429940

Published: 1 October 1999

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KEYWORDS

Brain

Scattering

Optical amplifiers

Modulation

Neuroimaging

Cerebral cortex

Optical fibers

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