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As we arrive at the 50th anniversary of the first computed tomography (CT) scan of a
live patient, we take this opportunity to revisit the history of early CT development. It is not an
exaggeration to say that the invention of CT may represent the greatest revolution in medical
imaging since the discovery of x-rays. We cover events over a period of about two decades that
started with the realization that accurate cross-sectional soft-tissue detail is possible and could be
a significant advance. We describe in some detail the development of the first CT system and
then the rapid technical advances during the following years that included the entry of many
companies into the field and the circumstances that led many of those entrants to exit the field.
Rather than focusing on the specific technical details (which can be found elsewhere), we include
stories and events in the hope that broader lessons can be learned. As the first x-ray-based digital
imaging modality, CT brought into common use an exceptional tool that benefits countless
patients every day. It also introduced dramatic changes to biomedical imaging as a field that
continues to influence progress to this day.
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Raymond A. Schulz, Jay A. Stein, Norbert J. Pelc, "How CT happened: the early development of medical computed tomography," J. Med. Imag. 8(5) 052110 (29 October 2021) https://doi.org/10.1117/1.JMI.8.5.052110