Label noise is inevitable in medical image databases, which can degrade the actual performance of supervised deep learning models and can bias the model's evaluation. Existing literature show that label noise in one class has minimal impact on model’s performance for another class in natural image classification problems where different target classes have relatively distinct shape and share minimal visual cues for knowledge transfer among the classes. However, it is not clear how class-dependent label noise affects the model’s performance when operating on medical images, for which different output classes can be difficult to distinguish even for experts, and there is a high possibility of knowledge transfer across classes during the training period. We hypothesize and investigate that for medical image classification tasks where different classes share very similar shape with differences only in texture, the noisy label for one class might affect the performance across other classes.
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