Mr. Brent A. Bell Profile

Brent A. Bell

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Author

Publications (12)

SPIE Journal Paper | 15 April 2013 Open Access

Optical coherence tomography for assessment of microbicide safety in a small animal model

Brent Bell, Kathleen Vincent, Nigel Bourne, Gracie Vargas, Massoud Motamedi

JBO, Vol. 18, Issue 04, 046010, (April 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.4.046010

KEYWORDS: Optical coherence tomography, Tissues, Animal model studies, In vivo imaging, Safety, Imaging systems, Tissue optics, Photomicroscopy, Toxicity, Visualization

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SPIE Journal Paper | 1 March 2010 Open Access

Optoacoustic imaging of the prostate: development toward image-guided biopsy

Mohammad Yaseen, Sergey Ermilov, Hans-Peter Brecht, Richard Su, André Conjusteau, Matthew Fronheiser, Brent Bell, Massoud Motamedi, Alexander Oraevsky

JBO, Vol. 15, Issue 02, 021310, (March 2010) https://doi.org/10.1117/12.10.1117/1.3333548

KEYWORDS: Prostate, Tissues, Acoustics, Tissue optics, Signal detection, Biopsy, In vivo imaging, Imaging systems, Tumors, Signal processing

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Proceedings Article | 6 March 2006 Paper

In vivo testing of laser optoacoustic system for image-guided biopsy of prostate

Alexander Oraevsky, Sergey Ermilov, Ketan Mehta, Tom Miller, Brent Bell, Eduardo Orihuela, Massoud Motamedi

Proceedings Volume 6086, 60860B (2006) https://doi.org/10.1117/12.658295

KEYWORDS: Prostate, Transducers, Blood, Tumors, Ultrasonography, Ultrasonics, Signal detection, Tissues, Reconstruction algorithms, Acoustics

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Proceedings Article | 24 October 2001 Paper

Optoacoustic images of early cancer in forward and backward modes

Alexander Karabutov, Valeri Andreev, Brent Bell, R. Declan Fleming, Zoran Gatalica, Massoud Motamedi, Elena Savateeva, Harbans Singh, Sergey Solomatin, Sharon Thomsen, P. Henrichs, Alexander Oraevsky

Proceedings Volume 4434, (2001) https://doi.org/10.1117/12.446687

KEYWORDS: Tissues, Transducers, Tumors, Ultrasonics, Breast, Tissue optics, Cancer, Acoustics, Absorption, Natural surfaces

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Proceedings Article | 4 June 2001 Paper

Development of an endoscopic fluorescence image-guided OCT probe for oral cancer detection

Roger McNichols, Ashok Gowda, Brent Bell, Richard Johnigan, Karen Calhoun, Massoud Motamedi

Proceedings Volume 4254, (2001) https://doi.org/10.1117/12.427941

KEYWORDS: Optical coherence tomography, Luminescence, Cancer, Tissues, Imaging systems, Tissue optics, Tumor growth modeling, Endoscopy, Biopsy, Mirrors

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Proceedings Article | 19 May 2000 Paper

Noninvasive detection and staging of oral cancer in vivo with confocal optoacoustic tomography

Elena Savateeva, Alexander Karabutov, Massoud Motamedi, Brent Bell, Richard Johnigan, Alexander Oraevsky

Proceedings Volume 3916, (2000) https://doi.org/10.1117/12.386341

KEYWORDS: Signal detection, Transducers, Acoustics, Tissue optics, Cancer, Thin film coatings, Tissues, Absorption, Confocal microscopy, Laser tissue interaction

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Proceedings Article | 15 July 1999 Paper

Optoacoustic imaging of oral cancer: feasibility studies in hamster model of squamous cell carcinoma

Alexander Oraevsky, Alexander Karabutov, Elena Savateeva, Brent Bell, Massoud Motamedi, Sharon Thomsen, Pankaj Jay Pasricha

Proceedings Volume 3597, (1999) https://doi.org/10.1117/12.356791

KEYWORDS: Tissues, Cancer, Transducers, Tissue optics, Natural surfaces, Tomography, Laser tissue interaction, Ultrasonics, Acoustics, Tumor growth modeling

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Proceedings Article | 22 May 1997 Paper

Delivery of intramyocardial diffused laser light for treatment of postinfarction ventricular tachycardia

David Ware, Chunjie Yang, Ashok Gowda, Brent Bell, Paul Boor, Massoud Motamedi

Proceedings Volume 2970, (1997) https://doi.org/10.1117/12.275029

KEYWORDS: Tissues, Optical fibers, Laser coagulation, Tissue optics, Semiconductor lasers, Heart, Natural surfaces, Injuries, Photons, Light scattering

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Proceedings Article | 15 May 1997 Paper

Rapid ablation of dental hard tissue using promoter-assisted pulsed Nd:YAG laser

Christopher Frederickson, Quiang Lu, Donald Hayes, David Wallace, Michael Grove, Brent Bell, Massoud Motamedi, Sohi Rastegar, C. Wright, Charles Arcoria

Proceedings Volume 2973, (1997) https://doi.org/10.1117/12.273582

KEYWORDS: Laser ablation, Teeth, Nd:YAG lasers, Pulsed laser operation, Laser dentistry, Absorption, Laser tissue interaction, Carbon, Er:YAG lasers, Ferroelectric materials

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Proceedings Article | 22 May 1995 Paper

Ultrasonic detection of photothermal interaction of lasers with tissue using a pulsed Doppler system

Hao Ying, Aamer Azeemi, Craig Hartley, Massoud Motamedi, Brent Bell, Sohi Rastegar, L. Sheppard

Proceedings Volume 2391, (1995) https://doi.org/10.1117/12.209918

KEYWORDS: Tissues, Laser tissue interaction, Doppler effect, Ultrasonography, Phase shift keying, Laser therapeutics, Pulsed laser operation, Ultrasonics, Microwave radiation, Transducers

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Thermal therapy using various heating sources such as lasers or microwaves to destroy benign and malignant lesions has recently gained widespread acceptance. However, the accurate prediction of thermal damage in tissue according to theoretical or computer modeling is difficult and unreliable due to target variability with respect to physical properties, geometry, and blood perfusion. Thus, one of the major obstacles to application of thermal therapies has been the lack of a noninvasive, real-time method that could determine the extent and geometry of treated tissue. To evaluate the effects of laser heating on tissue, we have developed an analog-digital hybrid Doppler ultrasound system to measure the phase and amplitude of ultrasonic echoes returned from the heated tissue. The system consists of an eight-gate pulsed Doppler detector, a 16-channel 12-bit A/D converter, and a signal analysis and visualization software package. In vitro studies using canine liver showed two distinct types of modulation of the echoes along the ultrasound beam path during laser irradiation using an 810 nm diode laser. Type 1 signals showed a small and slow variation in amplitude and phase, and were attributed to tissue coagulation. Type 1 signals showed a small and slow variation in amplitude and phase, and were attributed to tissue coagulation. Type 2 signals showed large and rapid variations in amplitude and phase which usually appeared after tissue surface explosion and were indicative of tissue ablation. We hypothesize that the observed phase changes in type 1 signals are due to thermal effects within the tissue consistent with tissue expansion and contraction while the phase changes in type 2 signals are likely due to formation and motion of gas bubbles in the tissue. A further development of the Doppler ultrasound technique could lead to the generation of feedback information needed for monitoring and automatic control of thermal treatment using various heating modalities such as laser, high intensity focused ultrasound, microwaves, or radio frequency waves.

Proceedings Article | 17 August 1994 Paper

Microjet-assisted dye-enhanced diode laser ablation of cartilaginous tissue

John Pohl, Brent Bell, Massoud Motamedi, Christopher Frederickson, David Wallace, Donald Hayes, Daniel Cowan

Proceedings Volume 2134, (1994) https://doi.org/10.1117/12.182951

KEYWORDS: Laser tissue interaction, Laser ablation, Semiconductor lasers, Tissues, Laser induced damage, Laser development, Indocyanine green, Spatial resolution, Optical properties, Tissue optics

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Proceedings Article | 12 July 1994 Paper

First report on application of diode laser for photocoagulation of canine myocardium

David Ware, Massoud Motamedi, John Pohl, Brent Bell, Paul Boor

Proceedings Volume 2130, (1994) https://doi.org/10.1117/12.179924

KEYWORDS: Semiconductor lasers, Laser tissue interaction, Laser coagulation, In vivo imaging, In vitro testing, Natural surfaces, Heart, Optical fibers, Tissues, Nd:YAG lasers

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Showing 5 of 12 publications

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