The importance of telemedicine using home healthcare system comes to the fore due to the COVID-19. Smartphone-based system can be a proper home healthcare tool for the diagnosis of early stages of diseases due to its portability, easy to use, and cost-effectiveness. Dental caries (DC) is one of the most common and serious diseases in dentistry. In the early stage of DC, white spot lesions (WSLs) can be observed. To detect WSLs, we demonstrate a smartphone-based multimode imaging system (SMIS) for the quantitative diagnosis of early DC. SMIS can offer RGB color, polarization, fluorescence, and multispectral imaging.
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