The possibility of using the laser Doppler flowmetry (LDF) method for the diagnosis of masked hypertension is considered. Significant trends in changes in parameters between groups of volunteers were identified. This indicates the possibility of using the LDF method to make decisions about the further follow-up of patients for the presence of a hidden increase in BP.
The possibility of using a multi-modal approach in the clinical practice of a dermatologist for psoriasis, which includes 3 optical non-invasive technologies: laser Doppler flowmetry, video capillaroscopy, and laser speckle-contrast imaging, is demonstrated. The dynamics of changes in the main microhemodynamic parameters of the microcirculatory bed of patients with psoriasis during conservative therapy was studied, and the effectiveness of treatment of patients suffering from psoriasis was evaluated.
The paper presents the results of in vivo experimental measurements of the endogenous fluorescence and blood perfusion in common bile duct tissues in obstructive jaundice patients during minimally invasive surgical operations. Nowadays the type of interventions become more widespread for treating hepatopancreatobiliary pathologies. An effective feedback which can be established by one or more optical diagnostic channels integrated into the standard instruments for minimally invasive manipulations would be of particular value to practical surgeons. To collect reference data, an experimental study has been conducted using a fiber optical probe with fluorescence spectroscopy and laser Doppler flowmetry channels. For every measurement, the areas of interest were different areas of common bile duct obstructed by a malignant tumor. Obtained results demonstrated significant variety registered intensities of fluorescence spectra and values of blood perfusion. Tested fiber optical endoscopic system showed sensitivity to the tissue state in the investigated area, so the two modal approach seems to be promising for further research and implementation in clinical practice.
Local hemodynamic parameters were studied by means of laser Doppler flowmetry in 15 patients with psoriasis in the stationary stage, who have plaques on the inner surface of the forearm.
LDF signals recorded at the site of psoriatic lesions of the tissue as well as in the intact tissue at a distance of 1-2 cm from the affected area were analysed. LDF signals were postprocessed by continuous wavelet transform using the Morlet wavelet.
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