Mr. Martin Oelschlägel Profile

Martin Oelschlägel

at TU Dresden

SPIE Involvement:

Author

Publications (2)

SPIE Journal Paper | 16 January 2025 Open Access

Comparative analysis of intraoperative thermal and optical imaging for identification of the human primary sensory cortex

Juliane Müller, Martin Oelschlägel, Stephan Sobottka, Matthias Kirsch, Gerald Steiner, Edmund Koch, Christian Schnabel

JBO, Vol. 30, Issue 01, 016002, (January 2025) https://doi.org/10.1117/12.10.1117/1.JBO.30.1.016002

KEYWORDS: Brain, Tumors, Optical imaging, Visualization, Surgery, Brain mapping, Biological research, Spatial resolution, Somatosensory cortex, Thermography

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SignificanceThe precise identification and preservation of functional brain areas during neurosurgery are crucial for optimizing surgical outcomes and minimizing postoperative deficits. Intraoperative imaging plays a vital role in this context, offering insights that guide surgeons in protecting critical cortical regions.AimWe aim to evaluate and compare the efficacy of intraoperative thermal imaging (ITI) and intraoperative optical imaging (IOI) in detecting the primary somatosensory cortex, providing a detailed assessment of their potential integration into surgical practice.ApproachData from nine patients undergoing tumor resection in the region of the somatosensory cortex were analyzed. Both IOI and ITI were employed simultaneously, with a specific focus on the areas identified as the primary somatosensory cortex (S1 region). The methodologies included a combination of imaging techniques during distinct phases of rest and stimulation, confirmed by electrophysiological monitoring of somatosensory evoked potentials to verify the functional areas identified by both imaging methods. The data were analyzed using a Fourier-based analytical framework to distinguish physiological signals from background noise.ResultsBoth ITI and IOI successfully generated reliable activity maps following median nerve stimulation. IOI showed greater consistency across various clinical scenarios, including those involving cortical tumors. Quantitative analysis revealed that IOI could more effectively differentiate genuine neuronal activity from artifacts compared with ITI, which was occasionally prone to false positives in the presence of cortical abnormalities.ConclusionsITI and IOI produce comparable functional maps with moderate agreement in Cohen’s kappa values. Their distinct physiological mechanisms suggest complementary use in specific clinical scenarios, such as cortical tumors or impaired neurovascular coupling. IOI excels in spatial resolution and mapping reliability, whereas ITI provides additional insights into metabolic changes and tissue properties, especially in pathological areas. Combined, these modalities could enhance the understanding and analysis of functional and pathological processes in complex neurosurgical cases.

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Proceedings Article | 17 March 2020 Presentation

Intraoperative thermographic perfusion mapping in neurosurgery using regularized semiparametric regression (Conference Presentation)

Juliane Müller, Nico Hoffmann, Martin Oelschlägel, Christian Schnabel, Gerald Steiner, Edmund Koch, Stephan B. Sobottka, Gabriele Schackert, Matthias Kirsch

Proceedings Volume 11315, 113150N (2020) https://doi.org/10.1117/12.2549641

KEYWORDS: Signal detection, Brain mapping, Interference (communication), Signal processing, Thermal modeling, Blood circulation, Surgery, Tissues, Thermography, Cerebral blood flow

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