The stratum corneum (SC), the outermost layer of the skin, plays a vital role in providing a barrier against dry environments. In order to understand the barrier function and overall condition of the skin, it is essential to assess the ability of the SC to absorb and retain water. In this study, we used stimulated Raman scattering (SRS) imaging to investigate the threedimensional SC structure and water distribution as water was absorbed into dried SC sheets. Our findings indicate that the process of water absorption and retention is dependent on the specific sample and can be spatially heterogeneous. These results demonstrate the potential of SRS imaging in diagnosing skin conditions.
Dermal blood vessels play a critical role in cutaneous homeostasis involved in the skin’s appearance. To elucidate the role of dermal vessels in skin beauty, we have been conducting many investigations with optical coherence tomography angiography (OCTA), whose use includes the analysis of skin’s superficial vascular plexuses.
This presentation will highlight some of our results and show the effects of the following three factors on both skin vascularity and appearance: Short-term ultraviolet ray exposure, solar lentigo and facial aging. From our studies, future applications of OCTA may be beneficial in the cosmetic and medical fields.
Aging alterations in dermal blood vessels have been investigated using Optical Coherence Tomography Angiography (OCTA). However, classifying the vessel’s type was previously limited. In this study, we focused on diameter-dependent vascular alterations in facial skin with age, developing 3D analytical methods to the OCTA data with removing tail-artifact. As a result, it was found that the number of micro-vessels, defined at 20–39 microns, decreased with age, which was inversely true for thick vessels (160–179 micron diameter). Our results suggest that the aging degree of dermal vessels may be uniquely assessed by the diameter-dependent vascular alterations using the OCTA.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.