Dr. Matthew W. Urban Profile

Dr. Matthew W. Urban

Associate Professor of Biomedical Engineering at Mayo Clinic

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Publications (8)

Proceedings Article | 12 March 2024 Presentation + Paper

Evaluating viscosity of thin layer fluid using acoustic radiation force-based optical coherence elastography

Hsiao-Chuan Liu, Matthew Urban

Proceedings Volume 12844, 1284402 (2024) https://doi.org/10.1117/12.3002133

KEYWORDS: Viscosity, Acoustic waves, Wave propagation, Elastography, Phase velocity, Optical coherence

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Proceedings Article | 15 March 2023 Presentation + Paper

Evaluating phase velocity of capillary waves on thin layer fluids using acoustic radiation force-based optical coherence elastography

Hsiao-Chuan Liu, Matthew Urban

Proceedings Volume 12381, 1238102 (2023) https://doi.org/10.1117/12.2650562

KEYWORDS: Phase velocity, Viscosity, Elastography, Wave propagation, Blood, Dispersion, Optical coherence tomography

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Proceedings Article | 15 March 2023 Presentation + Paper

Using dynamic optical coherence elastography to measure material properties

Matthew Urban, Hsiao-Chuan Liu, Piotr Kijanka

Proceedings Volume 12381, 1238109 (2023) https://doi.org/10.1117/12.2656407

KEYWORDS: Tissues, Elastography, Kidney, Ultrasonography, Biological samples, Optical coherence tomography, Materials properties, Optical coherence, Natural surfaces, Blood

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Proceedings Article | 2 March 2022 Paper

Two-dimensional (2D) harmonic oscillation optical coherence elastography

Hsiao-Chuan Liu, Matthew Urban

Proceedings Volume 11962, 1196204 (2022) https://doi.org/10.1117/12.2610036

KEYWORDS: Tissues, Elastography, Wave propagation, Tissue optics, Coherence (optics), Velocity measurements, Optical coherence tomography, Actuators, Wave plates, Optical filters

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Mechanical properties of tissues are an important indicator because they are associated with disease states. One of the common excitation sources in optical coherence elastography (OCE) to determine mechanical properties is acoustic radiation force (ARF). Using ARF as an excitation source requires a complicated focusing alignment, that potentially increases the difficulty for translational applications. Additionally, for tissue engineering applications, samples are usually cultured in a 35 mm Petri dish or 6-well cell culture plate. As the samples placed in a such limited space and with polystyrene material, using ARF as the excitation source could generate undesired reflected waves from rigid boundaries which affect the evaluation of mechanical properties, and acoustic energy for the ARF generation could be attenuated by the bottom of the plate. Here, we reported a new technique to evaluate the mechanical property of samples placed in 6- well cell culture plate without contacting the sample, named harmonic oscillation OCE. A homogeneous 5% gelatin phantom was fabricated and placed in a 6-well cell culture plate. The actuator was driven by a 300 Hz signal with a 15- cycle burst to vibrate the plate. The spectral domain optical coherence tomography (OCT) system was used to make measurements with 100 μm lateral spacing and 3.5 μm axial resolution within 10 mm × 10 mm field of view (FOV). An 8-angle directional filter and low pass filter were used to decompose two-dimensional (2D) wave propagations and undesired frequency components, respectively. The 2D wave velocities in each direction were separately evaluated by a 2D local wave velocity algorithm. The experimental results demonstrated that the averaged 2D wave velocity represents a good agreement with the dispersion analysis via the ARF excitation. The proposed harmonic oscillation OCE with an easy-to-setup approach can be used to evaluate 2D mechanical properties of samples placed in the 6-well cell culture plate without tedious focusing alignment or directly contacting samples, which provides largely potential applications for histopathological and tissue engineering communities.

Proceedings Article | 5 March 2021 Poster + Presentation + Paper

Four-dimensional (4D) phase velocity optical coherence elastography

Hsiao-Chuan Liu, Piotr Kijanka, Matthew Urban

Proceedings Volume 11645, 1164519 (2021) https://doi.org/10.1117/12.2576261

KEYWORDS: Phase velocity, Elastography, Tissue optics, Soft tissue optics, Coherence (optics), Tissues, Wave propagation, Visualization, Transducers, Mechanics

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Proceedings Article | 5 March 2021 Presentation + Paper

Characterizing mechanical properties of human blood clots using optical coherence elastography

Hsiao-Chuan Liu, Mehdi Abbasi, Yong Hong Ding, Tuhin Roy, Margherita Capriotti, Murthy Guddati, Ramanathan Kadirvel, David Kallmes, Waleed Brinjikji, Matthew Urban

Proceedings Volume 11645, 116450K (2021) https://doi.org/10.1117/12.2577975

KEYWORDS: Elastography, Coherence (optics), Blood, Acoustics, Wave propagation, Transducers, Optical coherence tomography, Brain

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Proceedings Article | 18 April 2017 Presentation + Paper

Development of an optically-based tension-indicating implanted orthopedic screw with a luminescent spectral ruler

Nakul Ravikumar, Melissa Rogalski, Donny Benza, Joshua Lake, Matthew Urban, Hunter Pelham, Jeffrey Anker, John DesJardins

Proceedings Volume 10081, 100810N (2017) https://doi.org/10.1117/12.2256052

KEYWORDS: Sensors, Luminescence, Head, Tissue optics, Cameras, X-ray optics, X-rays, Tissues, Bone, Computer programming

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Proceedings Article | 14 March 2009 Paper

Frequency compounding in multifrequency vibroacoustography

Matthew Urban, Azra Alizad, Mostafa Fatemi

Proceedings Volume 7265, 726511 (2009) https://doi.org/10.1117/12.811770

KEYWORDS: Acoustic emission, Ultrasonography, Image filtering, Breast, Tissues, In vivo imaging, Visualization, Optical filters, Acoustics, Metals

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Showing 5 of 8 publications

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