Dr. Michael Bouvet Profile

Dr. Michael Bouvet

Professor of Surgery at Univ of California San Diego

SPIE Involvement:

Conference Program Committee | Author

Publications (17)

Proceedings Article | 13 March 2024 Presentation

Development of imaging probes for fluorescence guided surgery of GI and endocrine tumors

Michael Bouvet

Proceedings Volume PC12825, PC128250X (2024) https://doi.org/10.1117/12.3009487

KEYWORDS: Tumors, Surgery, Fluorescence imaging, Fluorescence, Cancer, Pancreatic cancer, Colorectal cancer, Clinical trials, Antibodies, Animal model studies

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Proceedings Article | 17 March 2023 Presentation

Fluorescence conjugated anti-mucin antibodies to target and brightly label colorectal and pancreatic cancer

Kristin Cox, Michael Turner, Siamak Amirfakhri, Thinzar Lwin, Shanglei Liu, Robert Hoffman, Surinder Batra, Michael Bouvet

Proceedings Volume PC12361, PC123610I (2023) https://doi.org/10.1117/12.2650520

KEYWORDS: Pancreatic cancer, Luminescence, Colorectal cancer, Tumors, Mouse models, Cancer, Near infrared, Imaging systems, Colon, Visualization

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Proceedings Article | 15 March 2023 Presentation + Paper

Proceduralist criteria for evaluating interface utility of novel imaging modalities in early phase clinical trials: evaluating the need for standardized criteria

Eric Henderson, Jonathan Elliott, Shudong Jiang, I. Leah Gitajn, John Lee, Summer Gibbs, Michael Bouvet, Anita Mahadevan-Jansen, Michael Daly, Samuel Streeter, Keith Paulsen, Brian Pogue, Kimberley Samkoe, Sunil Singhal

Proceedings Volume 12361, 123610F (2023) https://doi.org/10.1117/12.2650756

KEYWORDS: Surgery, Tissues, Target recognition, Standards development, Visualization, Medical imaging, Imaging technologies, Clinical trials, Interfaces, Fluorophores

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Proceedings Article | 7 March 2022 Presentation

Fluorescent anti-CEA nanobody for rapid tumor-specific fluorescence labeling of patient-derived pancreatic cancer xenografts

Thinzar Lwin, Michael Turner, Nishino Hiroto, Sophie Hernot, Michael Bouvet

Proceedings Volume PC11943, PC1194307 (2022) https://doi.org/10.1117/12.2609973

KEYWORDS: Tumors, Pancreatic cancer, Luminescence, Molecules, Surgery, Tissues, Optical inspection, In vivo imaging, Field emission displays, Cancer

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Proceedings Article | 4 March 2022 Presentation + Paper

Precise tumor targeting and labeling with a flourescent mucin 4 antibody for imaging patient-derived pancreatic cancer in a mouse model

Michael Turner, Hiroto Nishino, Siamak Amirfakhri, Sukhwinder Kaur, Kavita Mallya, Robert Hoffman, Surinder Batra, Michael Bouvet

Proceedings Volume 11943, 1194305 (2022) https://doi.org/10.1117/12.2610524

KEYWORDS: Tumors, Pancreatic cancer, Surgery, Mouse models, Luminescence, Visualization, Medicine

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Proceedings Article | 4 March 2022 Presentation + Paper

Color-coded labeling of colon cancer liver metastasis and adjacent liver segment for image guided metastasectomy: a proof of concept review of clinical translatability

Hiroto Nishino, Michael Turner, Siamak Amirfakhri, Hannah Hollandsworth, Thinzar Lwin, Jun Yamamoto, Bérénice Framery, Françoise Cailler, Bernhard Singer, Robert Hoffman, Michael Bouvet

Proceedings Volume 11943, 1194306 (2022) https://doi.org/10.1117/12.2610557

KEYWORDS: Liver, Image segmentation, Tumors, Luminescence, Surgery, Visualization, Mouse models, Veins, Multichannel imaging systems, Indocyanine green

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SPIE Journal Paper | 28 June 2019 Open Access

Improved antibody-guided surgery with a near-infrared dye on a PEGylated linker for CEA-positive tumors

Paul Yazaki, Thinzar Lwin, Megan Minnix, Lin Li, Anakim Sherman, Justin Molnar, Aaron Miller, Paul Frankel, Junie Chea, Erasmus Poku, Nicole Bowles, Robert Hoffman, John Shively, Michael Bouvet

JBO, Vol. 24, Issue 06, 066012, (June 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.6.066012

KEYWORDS: Tumors, Surgery, Near infrared, Pancreatic cancer, Blood, Cancer, Luminescence, Tissues, Magnesium, In vivo imaging

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Proceedings Article | 7 March 2019 Presentation + Paper

Development of a humanized anti-CEA antibody for fluorescent guided surgery of GI cancers

Paul Yazaki, Thinzar Lwin, Megan Minnix , Lin Li, Anakim Sherman, Justin Molnar, Aaron Miller, Junie Chea, Erasmus Poku, Nicole Bowles, Robert Hoffman, John Shively, Michael Bouvet

Proceedings Volume 10862, 108620N (2019) https://doi.org/10.1117/12.2511771

KEYWORDS: Tumors, Surgery, Near infrared, Pancreatic cancer, Blood, Cancer, Tissues, In vivo imaging, Magnesium, Luminescence

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Proceedings Article | 1 March 2018 Presentation + Paper

Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model

Thinzar Lwin, Kentaro Miyake, Takashi Murakami, Jonathan DeLong, Paul Yazaki, John Shivley, Bryan Clary, Robert Hoffman, Michael Bouvet

Proceedings Volume 10478, 104780O (2018) https://doi.org/10.1117/12.2292546

KEYWORDS: Pancreatic cancer, Near infrared, Tumor growth modeling, In vivo imaging, Surgery

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Proceedings Article | 4 March 2016 Presentation + Paper

Fluorophore-conjugated antibodies for imaging and resection of GI tumors

Michael Bouvet, Robert Hoffman

Proceedings Volume 9696, 96960O (2016) https://doi.org/10.1117/12.2208811

KEYWORDS: Cancer, Surgery, Mouse models, Visualization, Luminescence, Signal detection, In vivo imaging, Pancreatic cancer, Colorectal cancer, Monoclonal antibodies, Tumors, Tissues, In vitro testing

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SPIE Journal Paper | 2 June 2014 Open Access

Specific tumor labeling enhanced by polyethylene glycol linkage of near infrared dyes conjugated to a chimeric anti-carcinoembryonic antigen antibody in a nude mouse model of human pancreatic cancer

Ali Maawy, Yukihiko Hiroshima, Yong Zhang, George Luiken, Robert Hoffman, Michael Bouvet

JBO, Vol. 19, Issue 10, 101504, (June 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.10.101504

KEYWORDS: Tumors, Near infrared, Pancreatic cancer, Liver, Mouse models, Lung, Tissues, Lymphatic system, Cancer, Surgery

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SPIE Journal Paper | 19 December 2013 Open Access

Comparison of a chimeric anti-carcinoembryonic antigen antibody conjugated with visible or near-infrared fluorescent dyes for imaging pancreatic cancer in orthotopic nude mouse models

Ali Maawy, Yukihiko Hiroshima, Sharmeela Kaushal, George Luiken, Robert Hoffman, Michael Bouvet

JBO, Vol. 18, Issue 12, 126016, (December 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.12.126016

KEYWORDS: Tumors, Luminescence, Pancreatic cancer, Tissues, Mouse models, Imaging systems, Cancer, Tumor growth modeling, Skin, Liver

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SPIE Journal Paper | 1 November 2010 Open Access

Enhancing magnetic resonance imaging tumor detection with fluorescence intensity and lifetime imaging

Ahmet Erten, David Hall, Carl Hoh, Hop Tran Cao, Sharmeela Kaushal, Sadik Esener, Robert Hoffman, Michael Bouvet, James Chen, Santosh Kesari, Milan Makale

JBO, Vol. 15, Issue 06, 066012, (November 2010) https://doi.org/10.1117/12.10.1117/1.3509111

KEYWORDS: Tumors, Magnetic resonance imaging, Luminescence, Cancer, Tissues, Neodymium, Resonance enhancement, Health sciences, Lanthanum, Fluorescence spectroscopy

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SPIE Journal Paper | 1 March 2009 Open Access

Extended-working-distance multiphoton micromanipulation microscope for deep-penetration imaging in live mice and tissue

Milan Makale, Michele McElroy, Peter O'Brien, Robert Hoffman, Sharon Guo, Michael Bouvet, Leo Barnes, Elizabeth Ingulli, David Cheresh

JBO, Vol. 14, Issue 02, 024032, (March 2009) https://doi.org/10.1117/12.10.1117/1.3103783

KEYWORDS: Microscopes, Imaging systems, Tumors, Objectives, Confocal microscopy, Lymphatic system, Tissues, Lenses, Sensors, Pancreas

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Proceedings Article | 29 February 2008 Paper

Imaging enhancement of malignancy by cyclophosphamide: surprising chemotherapy opposite effects

Kensuke Yamauchi, Meng Yang, Katsuhiro Hayashi, Ping Jiang, Mingxu Xu, Norio Yamamoto, Hiroyuki Tsuchiya, Katsuro Tomita, A. Moossa, Michael Bouvet, Robert Hoffman

Proceedings Volume 6868, 68680I (2008) https://doi.org/10.1117/12.772085

KEYWORDS: Cancer, Veins, Tumors, Liver, Lung, Colorectal cancer, In vivo imaging, Visualization, Green fluorescent protein, Liver cancer

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Proceedings Article | 13 February 2008 Paper

Subcellular real-time in vivo imaging of intralymphatic and intravascular cancer-cell trafficking

M. McElroy, K. Hayashi, S. Kaushal, M. Bouvet, Robert Hoffman

Proceedings Volume 6868, 68680J (2008) https://doi.org/10.1117/12.772120

KEYWORDS: Cancer, Lymphatic system, Skin, Imaging systems, Tumors, Real time imaging, Green fluorescent protein, Blood vessels, Skin cancer, In vivo imaging

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Proceedings Article | 14 February 2007 Paper

Preclinical fluorescent mouse models of pancreatic cancer

Michael Bouvet, Robert Hoffman

Proceedings Volume 6449, 64490X (2007) https://doi.org/10.1117/12.708060

KEYWORDS: Tumors, Pancreatic cancer, Tumor growth modeling, Visualization, Liver, Green fluorescent protein, Luminescence, Pancreas, Blood vessels, In vivo imaging

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