Authors considered the possibility of designing a non-invasive biomedical Raman spectrophotometer for the near infrared range using an ellipsoidal reflector as a collecting and focusing optical element to evaluation the biological media components, particularly glucose level. The technical solution for creating the spectrophotometer and its prototype are presented in this paper. The research of the experimental setup was observed faster and more sensitive photodetector reaction to the dynamic blood glucose changes of concentration. Practical testing was carried out by the Raman shift signal measuring on healthy volunteers at different time intervals with food intake associated. The experimental setup principles can be used to design a portable non-invasive glucometer or to quantitatively analyses the chemical composition of biological objects by changing Raman filters.
The work is devoted to the analysis of tools for the research of the indicatrix of scattering optical radiation by biological objects and their systematization. Simulation of system of spatial photometry for biomedical diagnostics which is designed to research the scattering within the solid angle 4π and the system of determining the optimal photometric distance of various biological structures were made.
In this work were considered photometric tools for biomedical diagnostics, which contain a mirror ellipsoid of revolution. Proposed schemes with ellipsoidal reflectors for diagnostics in reflected and in reflected and transmitted light. A comparative analysis of measurement standards scattering surfaces was held.
Possibilities of measuring systems that uses ellipsoidal reflectors for determining the
optical parameters of biological tissue are studied. The modified inverse Monte Carlo method was
designed for biomedical photometric system “biological tissue - ellipsoidal mirror.”
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