Endoscopic Optical Coherence Tomography (OCT) enables the assessment of the eardrum and the middle ear in vivo. However, revealing the ossicles is often limited due to shadowing effects of preceding structures and the 3D impression is difficult to interpret. To compare the identified middle ear structures, OCT and cone-beam CT of a patient were spatially aligned and showed a good agreement in locating malleus and the promontory wall. As CT imaging uses ionizing radiation and is thus limited in application, we furthermore provide a concept how radiology can be utilized as a priori knowledge for OCT imaging. Therefore, a statistical shape model derived from μCT data of temporal bone specimens was fitted to in vivo OCT measurements, potentially providing a real-time augmentation of endoscopic OCT for middle ear diagnostics in the future.
Endoscopic optical coherence tomography (OCT) enables the assessment of the eardrum and the middle ear in vivo. However, revealing the ossicles is often limited due to shadowing effects of preceding structures and the 3D impression is difficult to interpret. To compare the identified middle ear structures, OCT and cone-beam CT of a patient were spatially aligned and showed a good agreement in locating malleus and the promontory wall. As CT imaging uses ionizing radiation and is thus limited in application, we furthermore provide a concept how radiology can be utilized as a priori knowledge for OCT imaging. Therefore, a statistical shape model derived from μCT data of temporal bone specimens was fitted to in vivo OCT measurements, potentially providing a real-time augmentation of endoscopic OCT for middle ear diagnostics in the future.
Pathological alterations of the connective tissue, e.g. in succession of chronic otitis media, impair the acousto-mechanical function of the tympanic membrane (TM). Currently, none of the diagnostic techniques used in clinical practice assesses these tissue changes. By applying polarization-sensitive optical coherence tomography (PSOCT), a depth-resolved imaging technique providing additional tissue-specific contrast, local polarization changes of the fibrous layers of a human TM ex vivo were detected due to the birefringence of collagen fibers. Reconstructing and displaying local retardation from single-input PSOCT measurements enables to distinguish different tissue types which reveals the potential of PSOCT to extend conventional ENT diagnostics.
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