Quantitative images showing the speed of sound profile of the breast may be obtained by employing full-waveform inversion (FWI) methods on the measured data. These reconstruction methods work well for both dense and normal breasts. Contrast source inversion (CSI) is a frequency domain FWI method. In literature, many examples of successful application of CSI for breast imaging can be found. However, all these works are based on simulated data. In this work, we will present our first results obtained with employing CSI on experimental data. CSI was developed by Delft University of Technology and the experimental data was provided by FUJIFILM Healthcare Corporation. The experimental data is obtained using a ring-shaped transducer which scans a breast-mimicking gelatine phantom. Our initial results obtained with CSI look promising; all inclusions within the phantom are accurately reconstructed.
Breast cancer is the most common form of cancer diagnosed with women. To reduce its mortality rate, early diagnosis is important. In the past, this has led to the introduction of national screening programs using mammography. The disadvantages of mammography (application of ionizing radiation and low detection rate in dense breast) resulted in the demand for an alternative. This demand has led to the development of ultrasonic water bath scanning systems. Those systems scan the breast from all sides and aim for reconstructing the acoustic tissue properties from the measured pressure fields by employing among others full-waveform inversion methods. However, full-wave inversion is computationally expensive, especially in 3-D, and scales almost linear with the size of the spatial domain. To reduce the computational load, we propose a method that reduces the size of the spatial computational domain by back-propagating the field measured on the surface of the 3-D scanning geometry to a surface enclosing a reduced volume. To this end, the measured field is first decomposed into spherical Hankel functions with complex coefficients and subsequently redatumed to a new surface closer by the object. The proposed redatuming method is tested successfully for 3-D synthetic examples.
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