Ms. Ying Luo Profile

Ying Luo

at Univ of Virginia

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Proceedings Article | 19 May 2006 Paper

Simulations of retinal-based electronic components for application to THz frequency sensing platforms

Ying Luo, Dwight Woolard, Boris Gelmont, Hui Liu

Proceedings Volume 6212, 621202 (2006) https://doi.org/10.1117/12.664562

KEYWORDS: Gold, Molecules, Terahertz radiation, Nanostructures, Molecular electronics, Semiconductors, Optical filters, Sensors, Nanolithography, Far infrared

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The electro-optical properties of organic and bio-molecules have been previously investigated that have potential for selectively filtering and controlling the transmission of electromagnetic signals with carrier frequency in the THz band. Specifically, retinal isomers have been studied because they exhibit the type of THz characteristics needed for the design of molecular electronic devices. Here, the goal is to define bio-molecular filters that have utility in integrated platforms for sensing THz spectral signatures. According to our calculations, retinal isomers demonstrate the type of properties needed for the design of molecule-based optically-controllable filters in THz region. An initial challenge for this type of bio-architecture is the integration of the retinal-based components into conventional semiconductor devices. This paper presents a potential methodology for achieving such integrated sensor components. In particular, by modifying one end of retinal with a thiol linker, it is possible to chemically graft the retinal to gold surfaces. Therefore, since two-dimensional gold nanostructure arrays can be produced by depositing gold onto pit-patterned highly oriented pyrolytic graphite (HOPG) surface or semiconductor substrates, this approach could be applied to achieve large-scale integration of bio-molecular devices. This paper will report on simulations of ground state and metastable state energies, along with the associated THz spectra of the retinal isomeric molecule connected to a gold atom via the link of a cysteine molecule. In addition to the retinal isomers, this paper also investigates another isomer trans- and cis- stilbene and presents results suggesting that stilbene may also be a good candidate for molecular electronics. Hence, this paper provides results for the THz spectral characteristics and required optical excitations for a novel type of bio-device for sensing.

Proceedings Article | 18 May 2005 Paper

A bio-molecular inspired electronic architecture: bio-based device concepts for enhanced sensing

Dwight Woolard, Ying Luo, Boris Gelmont, Tatiana Globus, James Jensen

Proceedings Volume 5790, (2005) https://doi.org/10.1117/12.601029

KEYWORDS: Terahertz radiation, Molecules, Absorption, Biosensing, Phonons, Sensors, Computer architecture, Spectroscopy, Electronic components, Telecommunications

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A biological(bio)-molecular inspired electronic architecture is presented that offers the potential for defining nanoscale sensor platforms with enhanced capabilities for sensing terahertz (THz) frequency bio-signatures. This architecture makes strategic use of integrated biological elements to enable communication and high-level function within densely-packed nanoelectronic systems. In particular, this architecture introduces a new paradigm for establishing hybrid Electro-THz-Optical (ETO) communication channels where the THz-frequency spectral characteristics that are uniquely associated with the embedded bio-molecules are utilized directly. Since the functionality of this architecture is built upon the spectral characteristics of bio-molecules, this immediately allows for defining new methods for enhanced sensing of THz bio-signatures. First, this integrated sensor concept greatly facilitates the collection of THz bio-signatures associated with embedded bio-molecules via interactions with the time-dependent signals propagating through the nanoelectronic circuit. Second, it leads to a new Multi-State Spectral Sensing (MS3) approach where bio-signature information can be collected from multiple metastable state conformations. This paper will also introduce a new class of prototype devices that utilize THz-sensitive bio-molecules to achieve molecular-level sensing and functionality. Here, new simulation results are presented for a class of bio-molecular components that exhibit the prescribed type of ETO characteristics required for realizing integrated sensor platforms. Most noteworthy, this research derives THz spectral bio-signatures for organic molecules that are amenable to photo-induced metastable-state conformations and establishes an initial scientific foundation and design blueprint for an enhanced THz bio-signature sensing capability.

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