Dr. Yongping Zheng Profile

Dr. Yongping Zheng

Assistant Professor at Hong Kong Polytechnic Univ

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Author

Publications (5)

Proceedings Article | 15 March 2018 Presentation

In-vivo three-dimensional optoacoustic molecular imaging of the synovial vasculature in a mouse model of knee joint osteoarthritis (Conference Presentation)

Zhongyu LIU, Xuan Wang, Manting Au, Duojia Li, Yongping Zheng, Chunxiao Luo, Limin Rong, Chunyi Wen

Proceedings Volume 10494, 104940L (2018) https://doi.org/10.1117/12.2299658

KEYWORDS: Mouse models, Molecular imaging, In vivo imaging, 3D image processing, 3D modeling, Ultrasonography, Surgery, Control systems, Doppler effect, Tissues

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SPIE Journal Paper | 20 May 2015 Open Access

Correction on the distortion of Scheimpflug imaging for dynamic central corneal thickness

Tianjie Li, Lei Tian, Like Wang, Ying Hon, Andrew Lam, Yifei Huang, Yuanyuan Wang, Yongping Zheng

JBO, Vol. 20, Issue 05, 056006, (May 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.5.056006

KEYWORDS: Cornea, Calibration, Distortion, Cameras, Refractive index, Distance measurement, Eye, Contact lenses, Visualization, Polymethylmethacrylate

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Proceedings Article | 26 February 2014 Paper

An OCT-based air suction-indentation probe for tissue elasticity measurement

Yongping Zheng, Like Wang, Tianjie Li, Yuanyuan Wang

Proceedings Volume 8946, 894611 (2014) https://doi.org/10.1117/12.2049254

KEYWORDS: Optical coherence tomography, Tissues, Surface plasmons, Reliability, Signal processing, Sensors, Tissue optics, Endoscopy, Statistical analysis, Fiber optics sensors

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Proceedings Article | 23 May 2003 Paper

Ultrasonic measurement of articular cartilage swelling: preliminary results

Yongping Zheng, Jun Shi, Sushil Patil, Ling Qin, Arthur Mak

Proceedings Volume 5035, (2003) https://doi.org/10.1117/12.479961

KEYWORDS: Ultrasonography, Tissues, Cartilage, Ultrasonics, Interfaces, Natural surfaces, Transducers, Bone, In vitro testing, Medicine

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Proceedings Article | 23 May 2003 Paper

Ultrasound elastomicroscopy for articular cartilage: from static to transient and 1D to 2D

Yongping Zheng, Sharon Bridal, Jun Shi, Amena Saied, Minghua Lu, Britta Jaffre, Arthur Mak, Pascal Laugier, Ling Qin

Proceedings Volume 5035, (2003) https://doi.org/10.1117/12.479896

KEYWORDS: Ultrasonography, Tissues, Bone, Cartilage, Transducers, Interfaces, Natural surfaces, Image compression, Signal processing, Ultrasonics

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Articular cartilage (AC) is a biological weight-bearing tissue covering the ends of articulating bones within synovial joints. Its function very much depends on the unique multi-layered structure and the depth-dependent material properties, which have not been well invetigated nondestructively. In this study, transient depth-dependent material properties of bovine patella cartilage were measured using ultrasound elastomicroscopy methods. A 50 MHz focused ultrasound transducer was used to collect A-mode ultrasound echoes from the articular cartilage during the compression and subsequent force-relaxation. The transient displacements of the cartilage tissues at different depths were calculated from the ultrasound echoes using a cross-correlation technique. It was observed that the strains in the superficial zone were much larger than those in the middle and deep zones as the equilibrium state was approached. The tissues inside the AC layer continued to move during the force-relaxation phase after the compression was completed. This process has been predicted by a biphasic theory. In this study, it has been verified experimentally. It was also observed that the tissue deformations at different depths of AC were much more evenly distributed before force-relaxation. AC specimens were also investigated using a 2D ultrasound elastomicroscopy system that included a 3D translating system for moving the ultrasound transducer over the specimens. B-mode RF ultrasound signals were collected from the specimens under different loading levels applied with a specially designed compressor. Preliminary results demonstrated that the scanning was repeatable with high correlation of radio frequency signals obtained from the same site during different scans when compression level was unchanged (R² > 0.97). Strains of the AC specimens were mapped using data collected with this ultrasound elastomicroscope. This system can also be potentially used for the assessment of other biological tissues, bioengineered tissues or biomaterials with fine structures.

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