In this paper, we applied Brillouin microscopy for the measurement of the lipid molecule properties in the liver tissues and successfully visualized the two-dimensional distribution of Brillouin shift in the liver tissue. Our results may lead to new insights into developing early diagnosis and elucidation of the mechanism of non-alcoholic fatty disease.
Photomixing of internal mode beat in a Kerr micro-resonator frequency comb (microcomb) is a potential method to generate CW-THz wave with ultra-high frequency, low phase noise, and practicability for next-generation wireless communication. Here, we generated a 560-GHz CW-THz wave by photomixing of a soliton microcomb generated from a Si3N4 micro-resonator (frequency spacing = 560 GHz) with a uni-traveling-carrier photodiode (UTC-PD). Then, we evaluate the phase noise characteristics of generated CW-THz waves.
One interesting feature of optical frequency comb (OFC) is a function of frequency conversion between region and electric regions. While such feature has been used for generation of correct electric signal in microwave or millimeter region, it can be further used for fiber biosensing; namely, biosensing OFC. In this paper, we demonstrated detection of SARS-CoV-2 antigen based on a combination of dual fiber combs, an intracavity multi-mode-interference fiber sensor, and sensor surface modification of SARS-CoV-2 antibody.
Spectroscopic polarimetry (SP) is a powerful tool for characterization of thin film, polarization optics, semiconductor, and so on. However, mechanical polarization modulation of broadband light hampers its application for dynamic monitoring of a sample. In this article, we demonstrate the dynamic SP with features of polarization-modulation-free polarimetry and spectrometer-free spectroscopy benefiting from dual-comb spectroscopy (DCS) using a pair of optical frequency combs (OFCs). Effectiveness of the proposed system is highlighted by visualizing the hysteresis property of dynamic response in a liquid-crystal-on-silicon spatial light modulator at a sampling rate of 105 Hz.
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