Polarization properties of anterior segment disorders of the eyes were evaluated using a fiber-based
polarization-sensitive Fourier-domain optical coherence tomography (PS-FD-OCT). The light source is a
superluminescent diode with a central wavelength of 840 nm, and bandwidth of 50 nm. Synchronized two
line-CCD cameras allow high-speed measurement of birefringence of retina (line rate 27.7 kHz), and the
sensitivity of the system is 100.7 dB. Birefringence of the optical fiber was compensated with the surface
reflection. Phase retardation and orientation of the birefringence were measured with a Jones matrix based
algorithm. The phase retardation map of the anterior segment was visualized as a depth-resolved
three-dimensional image in addition to the conventional cross sectional OCT image. In the polarization
image of the normal eye, striking polarization change was observed at the sclera. In the eyes with necrotizing
scleritis, abnormal thinning of the sclera could be confirmed. In the eyes after filtering glaucoma surgery,
polarization change in the conjunctiva due to the abnormal fibrosis after surgery could be observed.
PS-FD-OCT is an effective tool to understand the polarization properties of different types of pathological
changes in the anterior segment of the eye.
A two- and three- dimensional swept source optical coherence tomography (SS-OCT) system is demonstrated. This system uses 1.3 &mgr;m probe band, posesses a depth resolution of 14 &mgr;m, and operated at a sensitivity of 100 dB. This SS-OCT is capable of realtime display of two-dimensional OCT, and can take three-dimensional OCT with the measurement time of 2 s.
28 cases of 25 patients including 6 types of corneal diseases, 4 types of uveal diseases, 1 type of scleral disease and 3
types of glaucoma surgery are examined by this SS-OCT.
Corneal opacity is main pathological condition in many corneal diseases which cause
to loss of Visual acuity. In ocular surface clinics, it is important to assess the relationship
between corneal opacity and visual acuity because of patients Quality of Vision. In this
study, swept-source-OCT (SS-OCT) system was employed for imaging of the corneal
opacity disorder. The purpose of this study is to assess the SS-OCT system for the
corneal opacities as quantitative examination and to evaluate the algorithm of
keratectomy simulation. This algorithm provides the entire corneal opacity map and
demonstrated virtual PTK image with ablation profile.
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