A Charge Coupled Device Imaging System For Ophthalmology

R Wanda Rowe; Samuel Packer; James Rosen; Yves Bizais

doi:10.1117/12.939315

15 June 1984 A Charge Coupled Device Imaging System For Ophthalmology

R Wanda Rowe, Samuel Packer, James Rosen, Yves Bizais

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Proceedings Volume 0454, Application of Optical Instrumentation in Medicine XII; (1984) https://doi.org/10.1117/12.939315
Event: Application of Optical Instrumentation in Medicine XII, 1984, San Diego, United States

Abstract

A digital camera system has been constructed for obtaining reflectance images of the fundus of the eye with monochromatic light. Images at wavelengths in the visible and near infrared regions of the spectrum are recorded by a charge-coupled device array and transferred to a computer. A variety of image processing operations are performed to restore the pictures, correct for distortions in the image formation process, and extract new and diagnostically useful information. The steps involved in calibrating the system to permit quantitative measurement of fundus reflectance are discussed. Three clinically important applications of such a quantitative system are addressed: the characterization of changes in the optic nerve arising from glaucoma, the diagnosis of choroidal melanoma through spectral signatures, and the early detection and improved management of diabetic retinopathy by measurement of retinal tissue oxygen saturation.

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R Wanda Rowe, Samuel Packer, James Rosen, and Yves Bizais "A Charge Coupled Device Imaging System For Ophthalmology", Proc. SPIE 0454, Application of Optical Instrumentation in Medicine XII, (15 June 1984); https://doi.org/10.1117/12.939315

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