Non-contact quantification of laser micro-impulse in water by atomic force microscopy and its application for biomechanics

Yoichiroh Hosokawa

doi:10.1117/12.903239

23 December 2011 Non-contact quantification of laser micro-impulse in water by atomic force microscopy and its application for biomechanics

Yoichiroh Hosokawa

Author Affiliations +

Proceedings Volume 8204, Smart Nano-Micro Materials and Devices; 82041D (2011) https://doi.org/10.1117/12.903239
Event: SPIE Smart Nano + Micro Materials and Devices, 2011, Melbourne, Australia

Abstract

We developed a local force measurement system of a femtosecond laser-induced impulsive force, which is due to shock and stress waves generated by focusing an intense femtosecond laser into water with a highly numerical aperture objective lens. In this system, the force localized in micron-sized region was detected by bending movement of a cantilever of atomic force microscope (AFM). Here we calculated the bending movement of the AFM cantilever when the femtosecond laser is focused in water at the vicinity of the cantilever and the impulsive force is loaded on the cantilever. From the result, a method to estimate the total of the impulsive force at the laser focal point was suggested and applied to estimate intercellular adhesion strength.

Citation Download Citation

Yoichiroh Hosokawa "Non-contact quantification of laser micro-impulse in water by atomic force microscopy and its application for biomechanics", Proc. SPIE 8204, Smart Nano-Micro Materials and Devices, 82041D (23 December 2011); https://doi.org/10.1117/12.903239

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