Integrating optical diagnostics and PDT: image guided treatment of oral lesions using a handheld multichannel fluorescence probe

Jonathan P. Celli; Shakir Khan; Rongguang Liang; Tayyaba Hasan; Bilal Hussain; Shahid Ali Siddiqui; Syed A. Hasan

doi:10.1117/12.2672304

17 March 2023 Integrating optical diagnostics and PDT: image guided treatment of oral lesions using a handheld multichannel fluorescence probe

Jonathan P. Celli, Shakir Khan, Rongguang Liang, Tayyaba Hasan, Bilal Hussain, Shahid Ali Siddiqui, Syed A. Hasan

Author Affiliations +

Proceedings Volume PC12359, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXI; PC1235906 (2023) https://doi.org/10.1117/12.2672304
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

New technologies for oral cancer detection and timely treatment at the point of care are urgently needed in resource limited clinics in South Asia, which face some of the highest incidence and mortality rates for oral malignancy in the world. Building on previous success with a fiber-coupled intraoral PDT light delivery system we investigate here the implementation of an intraoral diagnostic fluorescence imaging tool for guidance and monitoring PDT response. Our results indicate the utility of this approach while also laying the groundwork for combining cancer screening and treatment with the same hardware going forward.

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Citation Download Citation

Jonathan P. Celli, Shakir Khan, Rongguang Liang, Tayyaba Hasan, Bilal Hussain, Shahid Ali Siddiqui, and Syed A. Hasan "Integrating optical diagnostics and PDT: image guided treatment of oral lesions using a handheld multichannel fluorescence probe", Proc. SPIE PC12359, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXI, PC1235906 (17 March 2023); https://doi.org/10.1117/12.2672304

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