Mobile health (m-Health) has emerged as a trend in modern health care, which request point-of-care test be done near patients’ side. In this paper, we report on smartphone based spectrometry platform including optical spectrometer (OS) and multispectral imager (MSI), aiming to fill the translational gap in spectroscopy technology from central laboratory to clinical field. Here, combining its integrated CMOS sensor with a simple dispersion element, smartphone turns into a smart spectrometer that is capable to detect both of the absorption and fluorescence spectrum of the sample. The proposed smartphone OS is an effective platform for biomarker quantification, which have been applied to quantitatively analyze the glucose levevl in urine. Besides, we established a smartphone MSI based on a bio-inspired MSI chip, which could image the sample in spatial and spectral domain simultaneously. To demonstrate the application potential of the smartphone MSI, it was applied to in-vivo skin lesion diagnose. The chemical analysis capability, portability and costeffectiveness endow the smartphone spectrometry platform a promising analytical tool for m-Health diagnose, from in vivo pathological diagnose to bio-chemical marker quantification.
We propose an innovative approach to fabricate microlasers by using nanoparticles and advanced self-assembly technique. The silica-based high-Q-factor porous microcavity is formed in the self-assembled process, then dye gain materials infiltrate into the cavity to support stimulated radiation. The laser spectrum has multiple peaks at ~600 nm waveband with threshold as low as 28 uJ/pulse.
A high-frequency signal sampling approach by combining with compressive sensing and random equivalent sampling technology is proposed. The proposed sampling method achieves ∼10 times faster equivalent sampling rate by utilizing three parallel sub-Nyquist low-rate analog-to-digital converters (TPSL-ADC). By the union of the optical electric-field sensor with wide dynamic range and the proposed TPSL-ADC sampling method, a complete high-frequency electric-field signal measurement system has been realized. The high-frequency electric-field signal with an equivalent sampling rate of 1 GS / s is captured by utilizing three parallel ADCs with sampling rates of ∼32.3, 31.3, and 30.3 MS / s, respectively. The effectiveness of the proposed electric-field sensing and detecting system has been experimentally demonstrated.
As for the issue of the rapid wavelength interrogation of optical fiber wavelength-encoded sensor, a demodulation method combining spectrum-to-time domain information mapping and photonics time stretch technology is proposed. Using group velocity dispersion effect of dispersive elements, the spectrum of optical pulse will be mapped to a temporal waveform whose intensity mimics the spectrum. The temporal waveform is further stretched in timescale so that it is slow enough to be captured by electronic analog-to-digital converter. The performance of the proposed demodulation method is experimentally demonstrated to demodulate a wavelength-encoded sensor.
We show that the surface properties of Au thin films on a glass prism, typical of the Krestchsmann setup for SPR generation, can be modified or tuned with optical exposure. The wetting properties of the film were investigated by measuring contact angles of water drops at room temperature T = 23 °C. These contact angle change with optical irradiation from below the film. This change corresponds to a maximum contact angle reduction of Δθc ~ 30° when a surface plasmon resonance (SPR) is excited. The variation in contact angle during drop evaporation is evaluated under different irradiation conditions.
The extrusion nozzles of three low cost desktop 3D printers are characterised using optical fibre Bragg gratings. Temperature profiles show remarkably consistent distributions pointing to operation as good quality micro-furnaces potentially not only for 3D printing but also optical fibre drawing.
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