Biosensors are a potent tool that are widely used for health care, environmental safety, to all the way for disease diagnostics. Conventional surface acoustic waves (SAW)-grade biosensors are effective, but they often suffer sensitivity challenges leading to false-negatives. Inspired by this, we developed an innovative tone burst interdigitated electrodes (TB-IDT)-based biosensing that utilizes a unique fashion of surface acoustic waves technique for the biosensing phenomena. The TB-IDT consists of varied amplitude and width of the electrodes over the length that covers a wider range of frequency and amplitude access enhancing the sensitivity by many folds. Unlike conventional SAW-grade sensors, the proposed sensor has multidirectional access for better reproducibility and sensitivity in exploring the anisotropic nature of the piezoelectric substrate. The biosensor is highly sensitive and applies to multiple disease biomarkers detection.
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