Plasmonic nanoheaters, have attracted great attention in nanomedicine, due to their ability to efficiently generate and control heat delivery at the nanoscale. There is a wide offer of nanostructures that provide with strong photothermal responses and heat delivery, however most of them deliver heat in a symmetric way or require a certain orientation with respect to the excitation source to perform adequately. Here, we will first present an overview of some novel designs, fully plasmonic or hybrid dielectric/plasmonic, capable of offering not only enhanced photothermal response but also directional heat delivery. The thermal enhancing mechanism rely on the excitation of either dipolar or anapolar modes, depending on the design [4]. In the rest of the talk, we will show some of our recent findings on the thermal performance of DNA origami-based structures, offering theoretical insights into their potential for photothermal therapy applications.
Janus nanoparticles, incorporating plasmonic materials, have become important in thermoplasmonics. Controlled by pulsed excitation lasers, these nanostructures transfer thermal energy through material-fluid interfaces, regulated by interfacial thermal conductance. Here, we will present our most recent results in revealing the influence of interfacial thermal conductance on the thermal relaxation of metal-polymer Janus nanoparticles that exhibit directional heat dissipation under pulsed illumination. In particular, we will discuss how neglecting the temperature dependence of thermophysical properties leads to an overestimation of the nanoparticle's temperature. We demonstrate the potential of gold/polymer semishell nanostructures as effective nanoheaters for photothermal therapies. Our findings can motivate the exploration of innovative strategies for efficient nanoheating platforms in temperature-controlled devices.
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