KEYWORDS: Tissues, Ultrasonography, Acoustics, Solids, Design and modelling, Acoustic waves, Ultrasonics, Numerical simulations, Medical imaging, Medical device development
Precise ultrasound focusing is often limited by the fixed focal points and narrow frequency ranges. In this study, we design and experimentally testify an acoustic meta-lens to facilitate ultrasound focusing in tissues, for potential applications in clinical ultrasound therapy. The proposed meta-lens is capable of focusing broadband ultrasound waves in the megahertz range, by adequately considering acoustic-structure interaction. The manipulation and focusing of ultrasound waves are achieved by inversely optimizing the unit cell parameters of the meta-lens using a genetic algorithm (GA). Both numerical simulation and experiment demonstrate that the inversely designed and GA-optimized meta-lens improves the focusing precision and acoustic energy delivery. In particular, the tunable focal point of the meta-lens enables the scanning of tissue sections without a need to move the meta-lens along soft tissues.
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