This course will explore such concepts as; hyper-ledger and distributed ledger architectures, cryptography/hashing/encryption algorithms, game theory, crowd sourcing, consensus algorithms, closed and open architectures, advanced hardware architectures (such as the graphics processing units of the of the cryptocurrency mining equipment), smart-contracts, and centralized vs distributed autonomous authority. In addition to the traditional blockchain architectures, this course will cover the explosive interest in smart contract constructs that have been enabled by such things as the Ethereum Network and have been key enablers of Distributed Autonomous Organizations. Discussions will focus on some novel applications of these concepts as well as the Initial Coin Offerings (ICO’s) which are empowering a new wave of entrepreneurs seeking venture capitalist funding. Students in the class will gain some hands-on experience with a smart contract through a framework known as The Distributed Autonomous Classroom, developed by DAX LLC. This tool offers an innovative classroom and training framework that is designed to educate a training community on the potential of blockchain technologies and distributed ledger systems through an experiential learning environment. In this framework, we will use the blockchain to teach the blockchain. Finally, the class will discuss the convergence of Artificial Intelligence with Blockchain and lead some discussions about the next generation of disruptive technologies in IoT and beyond. To conclude, we will discuss when it is appropriate and beneficial to use blockchain technologies vs the more traditional P2P security and communications protocols that have successfully secured numerous communication systems and distributed architectures.