In this study, aerosol deposition of nanoparticles on flat surfaces has been investigated by Langevin dynamics (LD)
accounting for Brownian’s diffusion and a fix translational velocity. The particles are assumed to drop one at a time and
had a monodisperse size distribution. The detailed morphology of the nanoparticle films was investigated as a function of
Pe number, the ratio between Brownian and translational displacement for different structural constrains. The porosity
was reduced with increasing Pe number from the diffusion to ballistic deposition limit. It was found that the simulation
constrains have a substantial impact on the resulting film structural properties. This was attributed to the multi-scale
porosity of these aerosol-deposited films.
KEYWORDS: Ion channels, Proteins, Head, 3D modeling, Electroluminescence, Finite element methods, Signal processing, Solids, Computer simulations, Heart
In order to eliminate limitations of existing experimental or computational methods (such as patch-clamp technique or molecular dynamic analysis) a finite element (FE) model for multi length-scale and time-scale investigation on the gating mechanism of mechanosensitive (MS) ion channels has been established. Gating force value (from typical patch clamping values) needed to activate Prokaryotic MS ion channels was applied as tensional force to the FE model of the lipid bilayer. Making use of the FE results, we have discussed the effects of the geometrical and the material properties of the Escherichia coli MscL mechanosensitive ion channel opening in relation to the membrane’s Young’s modulus (which will vary depending on the cell type or cholesterol density in an artificial membrane surrounding the MscL ion channel). The FE model has shown that when the cell membrane stiffens the required channel activation force increases considerably. This is in agreement with experimental results taken from the literature. In addition, the present study quantifies the relationship between the membrane stress distribution around a ‘hole’ for modeling purposes and the stress concentration in the place transmembrane proteins attached to the hole by applying an appropriate mesh refinement as well as well defining contact condition in these areas.
The size effect of SiC particles on microstructures and mechanical properties of SiCp/Al composites produced by spontaneous infiltration technology was investigated. In this study, samples of SiCp/Al composites were fabricated using aluminum alloy ZL101 as the matrix material, and SiC particles with different sizes as reinforcement particles. The microstructures and micro-deformation of the samples were analyzed using optical micrograph, scanning electron microscope, energy dispersive spectrometer and WDW-50 respectively. The results show that the SiC particles can distribute uniformly in the aluminum matrix using the proposed method. Examing samples with different SiC particle sizes, the sample with the largest size of particle can significantly decrease the mechanical properties of the composites. Tensile strength of SiCp/Al composite increases along with a decrease in the size of SiC particles, but the ductility of the composites decreases. It was found that an obviously toughness fossa appeared in the fracture surfaces of composites, which indicated it behaviors tearing and plastic deformation characteristics.
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