Colorectal cancer (CRC) is the third most common and the second most deadly type of cancer worldwide. Currently, early-stage CRC detection is hindered by the limited information gold standard screening and diagnostic procedures (colonoscopies) provide on tissue structural changes. Accuracy of early CRC detection during colonoscopy and CRC delineation during microsurgery can potentially be increased by adding tissue molecular information in real-time. We developed a molecular-sensitive tool capable of determining depth-resolved fluorophore and chromophore concentrations, as well as scattering properties from wavelength-resolved fluorescence spectra alone. Normal mucosa and CRC exhibited differences in elastin, flavin, bile and lipid concentrations.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.