Laser-induced lipolysis on adipose cells

Efrain Solarte; O. Gutierrez; Rodrigo Neira; J. Arroyave; Carolina Isaza; Hugo Ramirez; Aldo F. Rebolledo; Willian Criollo; C. Ortiz

doi:10.1117/12.589307

21 October 2004 Laser-induced lipolysis on adipose cells

Efrain Solarte, O. Gutierrez, Rodrigo Neira, J. Arroyave, Carolina Isaza, Hugo Ramirez, Aldo F. Rebolledo, Willian Criollo, C. Ortiz

Author Affiliations +

Proceedings Volume 5622, 5th Iberoamerican Meeting on Optics and 8th Latin American Meeting on Optics, Lasers, and Their Applications; (2004) https://doi.org/10.1117/12.589307
Event: 5th Iberoamerican Meeting on Optics and 8th Latin American Meeting on Optics, Lasers, and Their Applications, 2004, Porlamar, Venezuela

Abstract

Recently, a new liposuction technique, using a low-level laser (LLL) device and Ultrawet solution prior to the procedure, demonstrated the movement of fat from the inside to the outside of the adipocyte (Neira et al., 2002). To determine the mechanisms involved, we have performed Scanning and Transmission Electron Microscopy studies; Light transmittance measurements on adipocyte dilutions; and a study of laser light propagation in adipose tissue. This studies show: 1. Cellular membrane alterations. 2. LLL is capable to reach the deep adipose tissue layer, and 3. The tumescence solution enhances the light propagation by clearing the tissue. MRI studies demonstrated the appearance of fat on laser treated abdominal tissue. Besides, adipocytes were cultivated and irradiated to observe the effects on isolated cells. These last studies show: 1. 635 nm-laser alone is capable of mobilizing cholesterol from the cell membrane; this action is enhanced by the presence of adrenaline and lidocaine. 2. Intracellular fat is released from adipocytes by co joint action of adrenaline, aminophyline and 635 nm-laser. Results are consistent with a laser induced cellular process, which causes fat release from the adipocytes into the intercellular space, besides the modification of the cellular membranes.

Citation Download Citation

Efrain Solarte, O. Gutierrez, Rodrigo Neira, J. Arroyave, Carolina Isaza, Hugo Ramirez, Aldo F. Rebolledo, Willian Criollo, and C. Ortiz "Laser-induced lipolysis on adipose cells", Proc. SPIE 5622, 5th Iberoamerican Meeting on Optics and 8th Latin American Meeting on Optics, Lasers, and Their Applications, (21 October 2004); https://doi.org/10.1117/12.589307

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