Dr. Hailiang Huang Profile

Dr. Hailiang Huang

Postdoctoral Associate

SPIE Involvement:

Author

Area of Expertise:

Digital breast tomosynthesis , x-ray imaging , dual-energy imaging

Publications (20)

SPIE Journal Paper | 4 December 2024

Scatter correction for contrast-enhanced digital breast tomosynthesis with a dual-layer detector

Xiangyi Wu, Xiaoyu Duan, Hailiang Huang, Wei Zhao

JMI, Vol. 12, Issue S1, S13008, (December 2024) https://doi.org/10.1117/12.10.1117/1.JMI.12.S1.S13008

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PurposeContrast-enhanced digital breast tomosynthesis (CEDBT) highlights breast tumors with neo-angiogenesis. A recently proposed CEDBT system with a dual-layer (DL) flat-panel detector enables simultaneous acquisition of high-energy (HE) and low-energy (LE) projection images with a single exposure, which reduces acquisition time and eliminates motion artifacts. However, x-ray scatter degrades image quality and lesion detectability. We propose a practical method for accurate and robust scatter correction (SC) for DL-CEDBT.ApproachThe proposed hybrid SC method combines the advantages of a two-kernel iterative convolution method and an empirical interpolation strategy, which accounts for the reduced scatter from the peripheral breast region due to thickness roll-off and the scatter contribution from the region outside the breast. Scatter point spread functions were generated using Monte Carlo simulations with different breast glandular fractions, compressed thicknesses, and projection angles. Projection images and ground truth scatter maps of anthropomorphic digital breast phantoms were simulated to evaluate the performance of the proposed SC method and three other kernel- and interpolation-based methods. The mean absolute relative error (MARE) between scatter estimates and ground truth was used as the metric for SC accuracy.ResultsDL-CEDBT shows scatter characteristics different from dual-shot, primarily due to the two energy peaks of the incident spectrum and the structure of the DL detector. Compared with the other methods investigated, the proposed hybrid SC method showed superior accuracy and robustness, with MARE of ∼3.1% for all LE and HE projection images of different phantoms in both cranial-caudal and mediolateral-oblique views. After SC, cupping artifacts in the dual-energy image were removed, and the signal difference-to-noise ratio was improved by 82.0% for 8 mm iodine objects.ConclusionsA practical SC method was developed, which provided accurate and robust scatter estimates to improve image quality and lesion detectability for DL-CEDBT.

SPIE Journal Paper | 24 July 2024

In-silico study of the impact of system design parameters on microcalcification detection in wide-angle digital breast tomosynthesis

Xiaoyu Duan, Hailiang Huang, Wei Zhao

JMI, Vol. 12, Issue S1, S13002, (July 2024) https://doi.org/10.1117/12.10.1117/1.JMI.12.S1.S13002

KEYWORDS: Digital breast tomosynthesis, Signal to noise ratio, Imaging systems, Design, Sensors, Tunable filters, Breast, Quantum noise, Object detection, CMOS sensors

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Proceedings Article | 29 May 2024 Paper

Quantitative imaging of iodine-based contrast agent in dual-energy DBT

Emil Sidky, Xiangyi Wu, Xiaoyu Duan, Hailiang Huang, Wei Zhao, Leo Zhang, John Paul Phillips, Zheng Zhang, Buxin Chen, Dan Xia, Ingrid Reiser, Xiaochuan Pan

Proceedings Volume 13174, 1317402 (2024) https://doi.org/10.1117/12.3026587

KEYWORDS: Digital breast tomosynthesis, Contrast agents, Tumors, Reconstruction algorithms, Iodine, Image processing

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Proceedings Article | 29 May 2024 Paper

Cascaded system analysis of a direct-indirect dual-layer flat-panel-detector for contrast-enhanced breast imaging

Xiangyi Wu, Xiaoyu Duan, Hailiang Huang, Adrian Howansky, Wei Zhao

Proceedings Volume 13174, 131740V (2024) https://doi.org/10.1117/12.3024425

KEYWORDS: Detector development, Dual energy imaging, X ray detectors, Quantum noise, Image contrast enhancement, Modulation transfer functions, Imaging systems, Silver, Performance modeling, Breast imaging, X-rays, Quantum detection

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Proceedings Article | 29 May 2024 Paper

Experimental results of the first prototype direct-indirect dual-layer flat-panel detector for contrast-enhanced digital mammography and contrast-enhanced digital breast tomosynthesis

Xiaoyu Duan, Hailiang Huang, Salman Arnab, Yves Chevalier, Luc Laperrière, Wei Zhao

Proceedings Volume 13174, 1317405 (2024) https://doi.org/10.1117/12.3026916

KEYWORDS: Detector development, Object detection, Iodine, Breast, Prototyping, Digital mammography, Digital breast tomosynthesis

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SPIE Journal Paper | 15 May 2023

Comparison of lesion detection and conspicuity between narrow-angle and wide-angle digital breast tomosynthesis for dense and non-dense breasts

Hailiang Huang, David Scaduto, Anastasia Plaunova, Kim Rinaldi, Paul R. Fisher, Wei Zhao

JMI, Vol. 10, Issue S2, S22407, (May 2023) https://doi.org/10.1117/12.10.1117/1.JMI.10.S2.S22407

KEYWORDS: Digital breast tomosynthesis, Breast, Autoregressive models, Imaging systems, Quantum reading, Diagnostics, Breast density, Quantum noise, Tissues, Cancer detection

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Proceedings Article | 7 April 2023 Presentation + Paper

A scatter correction method for contrast-enhanced digital breast tomosynthesis with a dual-layer detector

Xiangyi Wu, Xiaoyu Duan, Hailiang Huang, Wei Zhao

Proceedings Volume 12463, 1246318 (2023) https://doi.org/10.1117/12.2654084

KEYWORDS: Breast, Convolution, Interpolation, Digital breast tomosynthesis, Monte Carlo methods, X-rays, Error analysis, Imaging systems, X-ray detectors, Image compression

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SPIE Journal Paper | 15 March 2023

Deep-learning convolutional neural network-based scatter correction for contrast enhanced digital breast tomosynthesis in both cranio-caudal and mediolateral-oblique views

Xiaoyu Duan, Pranjal Sahu, Hailiang Huang, Wei Zhao

JMI, Vol. 10, Issue S2, S22404, (March 2023) https://doi.org/10.1117/12.10.1117/1.JMI.10.S2.S22404

KEYWORDS: Breast, Monte Carlo methods, Education and training, Muscles, Polymethylmethacrylate, Lead, Convolutional neural networks, Chest, Digital breast tomosynthesis, Picosecond phenomena

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Proceedings Article | 4 April 2022 Presentation + Paper

Evaluation of a direct-indirect dual layer detector for contrast enhanced breast imaging: Monte Carlo simulations and physical experiments

Xiaoyu Duan, Adrian Howansky, Hailiang Huang, Wei Zhao

Proceedings Volume 12031, 120310A (2022) https://doi.org/10.1117/12.2613056

KEYWORDS: Dual energy imaging, Monte Carlo methods, Iodine, X-rays, Breast, Imaging systems

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Proceedings Article | 15 February 2021 Presentation + Paper

Strategies of improving lesion detection in wide-angle digital breast tomosynthesis (DBT) with angular dose distribution and detector design

Xiaoyu Duan, Hailiang Huang, Wei Zhao

Proceedings Volume 11595, 115951H (2021) https://doi.org/10.1117/12.2582480

KEYWORDS: Digital breast tomosynthesis, Sensors, CMOS sensors, Sensor performance, Breast, Tissues, Selenium, Imaging systems, Image enhancement, Image acquisition

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Proceedings Article | 15 February 2021 Presentation + Paper

Assessment of reproducibility of volumetric breast density measurement using dual energy digital breast tomosynthesis

Hailiang Huang, Xiaoyu Duan, Wei Zhao

Proceedings Volume 11595, 1159529 (2021) https://doi.org/10.1117/12.2582131

KEYWORDS: Breast, Digital breast tomosynthesis, Dual energy imaging, X-rays

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Proceedings Article | 22 May 2020 Paper

Effect of scatter correction on image noise in contrast-enhanced digital breast tomosynthesis

Hailiang Huang, Xiaoyu Duan, Pranjal Sahu, Wei Zhao

Proceedings Volume 11513, 115130J (2020) https://doi.org/10.1117/12.2561784

KEYWORDS: Breast, Digital breast tomosynthesis, Denoising, Digital imaging, Image quality

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Proceedings Article | 22 May 2020 Paper

Assessment of task-based performance from five clinical DBT systems using an anthropomorphic breast phantom

Lynda Ikejimba, Jesse Salad, Christian Graff, Mitchell Goodsitt, Heang-Ping Chan, Wei Zhao, Hailiang Huang, Bahaa Ghammraoui, Joseph Lo, Stephen Glick

Proceedings Volume 11513, 1151305 (2020) https://doi.org/10.1117/12.2564357

KEYWORDS: Digital breast tomosynthesis, Breast, Imaging systems, Inkjet technology, Printing, Mammography, Breast imaging, Tissues, Medicine, Roads

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Proceedings Article | 22 May 2020 Paper

Scatter correction with deep learning approach for contrast enhanced digital breast tomosynthesis (CEDBT) in both cranio-caudal (CC) view and mediolateral oblique (MLO) view

Xiaoyu Duan, Pranjal Sahu, Hailiang Huang, Wei Zhao

Proceedings Volume 11513, 115130Q (2020) https://doi.org/10.1117/12.2564358

KEYWORDS: Breast, Monte Carlo methods, Digital breast tomosynthesis, Dual energy imaging, Point spread functions, Computer simulations, Imaging systems, Convolutional neural networks

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Proceedings Article | 16 March 2020 Paper

Factors affecting microcalcification detection of wide-angle digital breast tomosynthesis and strategies for improving performance

Xiaoyu Duan, Hailiang Huang, Chloe Leigh Ong, Wei Zhao

Proceedings Volume 11312, 113120H (2020) https://doi.org/10.1117/12.2549864

KEYWORDS: Digital breast tomosynthesis, CMOS sensors, Breast, Monte Carlo methods, Visibility, Tissues, Modulation transfer functions, Image resolution, Signal detection

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Proceedings Article | 16 March 2020 Paper

Volumetric breast density estimation using dual energy digital breast tomosynthesis

Hailiang Huang, Xiaoyu Duan, Wei Zhao

Proceedings Volume 11312, 113120O (2020) https://doi.org/10.1117/12.2549645

KEYWORDS: Breast, Digital breast tomosynthesis, Dual energy imaging, X-rays, Breast cancer

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Proceedings Article | 7 March 2019 Paper

Effects of angular range on lesion margin assessment in contrast-enhanced digital breast tomosynthesis

Hailiang Huang, David Scaduto, Kim Rinaldi, Jingxuan Liu, Julia Wicklein, Mathias Hoernig, Thomas Mertelmeier, Paul Fisher, Wei Zhao

Proceedings Volume 10948, 1094840 (2019) https://doi.org/10.1117/12.2512243

KEYWORDS: Iodine, Digital breast tomosynthesis, Breast, Tumors, Biopsy, Dual energy imaging, Imaging systems, Breast cancer

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SPIE Journal Paper | 13 February 2019 Open Access

Comparison of contrast-enhanced digital mammography and contrast-enhanced digital breast tomosynthesis for lesion assessment

Hailiang Huang, David A. Scaduto, Chunling Liu, Jie Yang, Chencan Zhu, Kim Rinaldi, Jason Eisenberg, Jingxuan Liu, Mathias Hoernig, Julia Wicklein, Sebastian Vogt, Thomas Mertelmeier, Paul R. Fisher, Wei Zhao

JMI, Vol. 6, Issue 03, 031407, (February 2019) https://doi.org/10.1117/12.10.1117/1.JMI.6.3.031407

KEYWORDS: Breast, Digital breast tomosynthesis, Digital mammography, X-rays, Mammography, Biopsy, Medicine, Sensors, Image compression, Diagnostics

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Proceedings Article | 6 July 2018 Paper

Impact of angular range of digital breast tomosynthesis on mass detection in dense breasts

David Scaduto, Hailiang Huang, Chunling Liu, Kim Rinaldi, Axel Hebecker, Thomas Mertelmeier, Sebastian Vogt, Paul Fisher, Wei Zhao

Proceedings Volume 10718, 107181V (2018) https://doi.org/10.1117/12.2318243

KEYWORDS: Digital breast tomosynthesis, Breast, Autoregressive models, Mammography, Tissues, Reconstruction algorithms, Systems modeling, Cancer

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Proceedings Article | 6 July 2018 Paper

Lesion assessment and radiation dose in contrast-enhanced digital breast tomosynthesis

Hailiang Huang, David Scaduto, Chunling Liu, Jie Yang, Chencan Zhu, Kim Rinaldi, Jason Eisenberg, Jingxuan Liu, Mathias Hoernig, Julia Wicklein, Sebastian Vogt, Thomas Mertelmeier, Paul Fisher, Wei Zhao

Proceedings Volume 10718, 107181J (2018) https://doi.org/10.1117/12.2316371

KEYWORDS: Image contrast enhancement, Digital breast tomosynthesis, Breast, Biopsy, Digital mammography, Mammography, X-rays, Diagnostics, Image acquisition

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